Rules for Breakage

Quadrature Rules for Fuzzy Integrals

Calibration of Hardening Rules for Cyclic Plasticity

In the realm of multi-axial ratcheting, a step by step mathematical approach is developed for the parameter determination of decomposed kinematic hardening rules. For this purpose, key characteristics are mathematically derived for these hardening rules under multi-axial loading. These characteristics are then utilized to develop expressions which relate the loading history to the accumulated p...

GENERATING FUZZY RULES FOR PROTEIN CLASSIFICATION

This paper considers the generation of some interpretable fuzzy rules for assigning an amino acid sequence into the appropriate protein superfamily. Since the main objective of this classifier is the interpretability of rules, we have used the distribution of amino acids in the sequences of proteins as features. These features are the occurrence probabilities of six exchange groups in the seque...

Making chromosomes hot for breakage

Meiosis is a special cell division program that reduces the diploid chromosome set to a haploid set for sexual reproduction. Reductional segregation of homologous chromosomes is helped by physical linkages (crossovers) provided by recombina-tion. A long-standing problem in biology has been to understand how meiotic recom-bination is controlled, since its initiation by DNA double-strand breaks (...

Bone breakage

In This Issue In This Issue Saying NO to muscular dystrophy ccording to the prevailing model for Duchenne muscular dystrophy (DMD) pathogenesis, a lack of dystrophin protein makes muscle cells susceptible to mechanical damage, leading to muscle breakdown. On page 123, Wehling et al. suggest that the major damage in DMD may actually be caused by a secondary consequence of dystrophin loss: destru...